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Symbol
Name
ID
Klf3
Kruppel-like transcription factor 3 (basic)
MGI:1342773
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations

Mouse Phenotypes
cardiovascular system phenotype
abnormal ascending aorta morphology
abnormal ventricle myocardium morphology
increased atrioventricular cushion size
increased heart left atrium size
increased heart right atrium size
abnormal heart left atrium morphology
abnormal heart right atrium morphology
atrial septal defect
abnormal interventricular septum morphology
ventricular septal defect
increased heart weight
cardiac hypertrophy
abnormal aortic valve cusp morphology
bicuspid aortic valve
thick aortic valve cusps
aortic valve stenosis
abnormal heart left ventricle morphology
increased heart right ventricle size
abnormal blood flow velocity
hypervolemia
increased cardiac output
hematoma
abnormal blood pressure regulation
increased cardiac muscle contractility
tricuspid valve regurgitation
pulmonary valve regurgitation
decreased systemic arterial blood pressure
decreased mean systemic arterial blood pressure
hypotension
congestive heart failure
Availability Mouse Genotype
Klf3Gt(CH0516)Wtsi/Klf3Gt(CH0516)Wtsi *
Klf3Gt(XS0187)Wtsi/Klf3Gt(XS0187)Wtsi *
Klf3m1Cmhd/Klf3m1Cmhd
Klf3m1Cmhd/Klf3+ * !

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory